💉 GLP-1 Injection Price Comparison
Compare Mounjaro (tirzepatide) and Wegovy (semaglutide) prices across all UK providers
Oral GLP-1 Weight Loss Pills Now Available in the UK
Oral semaglutide weight loss pills have launched in the UK. Compare prices across providers using our Oral Pills tab.
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💊 Weight Loss Pills UK 2026
Compare prescription and over-the-counter weight loss tablets — prices, evidence and eligibility
| Medication | Type | From (monthly) | Eligibility | Evidence | Where to get |
|---|---|---|---|---|---|
| Rybelsus (oral semaglutide) | Oral GLP-1 | £149/mo | BMI 30+ or 27+ with condition | ~15% weight loss (STEP trials) | Online doctor / GP |
| Orlistat (Xenical/Alli) | Prescription | £17.49/mo | BMI 28+ with condition or 30+ | 5–7% weight loss at 12mo | GP / online pharmacy |
| Alli (OTC Orlistat) | Over Counter | £29.99/mo | BMI 28+ (self-assessed) | 5% weight loss with low-fat diet | Boots, Superdrug, Amazon |
| Naltrexone/Bupropion (Mysimba) | Prescription | £89/mo | BMI 30+ or 27+ with condition | 5–8% weight loss at 12mo | Specialist clinics / online doctor |
| Phentermine (not licensed UK) | Unlicensed | Not recommended | N/A | Limited / risk profile | Not available in UK |
Rybelsus (Oral Semaglutide)
The first oral GLP-1 medication approved for weight management in the UK. Same active ingredient as Wegovy injection but taken as a daily tablet. Available from online doctors from ~£149/month.
Orlistat (Prescription)
Blocks ~30% of dietary fat absorption. Available on NHS prescription or privately. Must be combined with a reduced-calorie diet to be effective. Most cost-effective prescription option available.
Alli (OTC Orlistat 60mg)
Lower-dose version of orlistat available without prescription from pharmacies. Reduces fat absorption, must be combined with a calorie-controlled low-fat diet. Half the prescription dose.
Mysimba (Naltrexone/Bupropion)
Combination pill that targets the brain's reward system to reduce appetite and food cravings. NICE-approved for adults with BMI 30+ or 27+ with weight-related conditions.
🥗 Meal Replacement Plan Comparison
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🏅 Slimming Club Comparison
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| Club | Format | Monthly cost | Annual cost | Trial | Best for | Rating |
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